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黄丝郁金中的生物碱和倍半萜类成分(英文)

Alkaloid and sesquiterpenes from the root tuber of Curcuma longa

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【作者】 王丽瑶张勉张朝凤王峥涛

【Author】 WANG Li-yao,ZHANG Mian,ZHANG Chao-feng,WANG Zheng-tao(Key Laboratory of Modern Chinese Medicines of China Pharmaceutical University,Ministry of Education;Research Department of Pharmacognosy,China Pharmaceutical University,Nanjing 210038,China)

【机构】 中国药科大学现代中药教育部重点实验室生药学研究室中国药科大学现代中药教育部重点实验室生药学研究室 江苏南京210038江苏南京210038

【摘要】 姜科植物姜黄(Curcuma longa)的块根称为黄丝郁金,是常用中药郁金的来源之一。为了研究黄丝郁金的利胆活性成分,采用柱色谱法对姜黄干燥块根的化学成分进行了研究。本文主要报道从中分离得到的1个喹啉类生物碱2-(2′-methyl-1′-propenyl)-4,6-dimethyl-7-hydroxyquinoline(1),7个没药烷型倍半萜2,5-dihydroxybisabola-3,10-diene(2),4,5-dihydroxybisabola-2,10-diene(3),turmeronol A(4),bisacurone(5),bisacurone A(6),bisacurone B(7)和bisacurone C(8),以及dehydrozingerone(9)和zingerone(10)的分离和鉴定。化合物1为一个新的生物碱类化合物,化合物6~8为首次从姜黄中分得,化合物9~10为首次从姜黄属植物中分离得到。

【Abstract】 One new quinoline alkaloid and seven known bisabolane sesquiterpenes: 2-(2′-methyl-1′-propenyl)-4,6-dimethyl-7-hydroxyquinoline(1),2,5-dihydroxybisabola-3,10-diene(2),4,5-dihydroxybisabola-2,10-diene(3),turmeronol A(4),bisacurone(5),bisacurone A(6),bisacurone B(7),bisacurone C(8),as well as dehydrozingerone(9) and zingerone(10) were isolated from the root tuber of Curcuma longa.Their structures were identified by spectral evidence.Compound 1 is a new compound,compounds 6-8 were isolated from this plant for the first time and compounds 9-10 from Curcuma for the first time.

【关键词】 姜黄生物碱倍半萜
【Key words】 Curcuma longaalkaloidsesquiterpene
  • 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,2008年07期
  • 【分类号】R284
  • 【被引频次】20
  • 【下载频次】515
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