【摘要】 [目的]了解引起呼吸系统感染的病原微生物种类和耐药性。[方法]采用梅里埃半自动细菌分析仪对济南市第五人民医院2005年1月至2007年12月住院病人痰标本进行病原鉴定和药敏试验。[结果]2005~2007年共检测痰标本1 039份,检出致病菌186株,检出率为17.90%。各年的检出率分别为16.8%、16.7%和17.2%,差异无统计学意义(P>0.05)。186株致病菌中,主要为铜绿假单胞菌44株(占23.66%)和肺炎克雷伯菌29株(占15.59%)。药敏试验铜绿假单胞菌对SMZ的耐药性最高为95.45%;肺炎克雷伯菌对青霉素的耐药性最高为100.00%;鲍氏不动杆菌除了亚胺培南(100.00%)敏感外,对其他抗生素的耐药率均在50%以上。[结论]引起呼吸系统感染的病原微生物主要是细菌,细菌的耐药性因细菌的种类不同耐药程度不一,应引起医院的重视。更多还原

【Abstract】 [Objective]To learn the species and drug resistance of pathogenic microorganism that caused respiratory system infection.[Methods]The phlegm specimens of hospitalized patients in the Fifth People’s Hospital of Ji’nan from January,2005 to December,2007,were examined for pathogen identification and drug sensitivity test with Merieux semi-automatic bacteria analyzer.[Results]A total of 1 039 phlegm specimens have been examined from 2005 to 2007,with 186 pathogenic bacteria detected.The detection rate was 17.90%.And the rate for the three years was 16.8%,16.7% and 17.2% respectively.There was no difference(P>0.05).Among the 186 pathogenic bacteria,the major pathogens included 44 p.aeruginosa(23.66%) and 29 klebsiella pneumoniae(15.59%).The drug sensitivity test showed that P.aeruginosa’s highest resistance rate to SMZ was 95.45% and klebsiella pneumoniae’s resistance rate to penicillin was 100.00%.Acinetobacter baumannii was sensitive to MERO(100%) and some other antibiotics(over 50%) as well.[Conclusion]The major pathogenic microorganism causing respiratory system infection was bacteria,of which drug resistance was different for diverse species.Therefore,close attention should be paid to this by the hospital.更多还原