【摘要】 目的:了解各医院及药品生产、经营企业的药品不良反应(ADR)监测情况,探讨发生ADR的相关因素。方法:采用横断面流行病学方描述法,分别对269例ADR患者的性别、年龄、单位分布、住院与门诊、药物种类、给药途径及临床表现进行统计分析。结果:269例ADR中,男女比为1.24:1,男性多于女性;20～29岁发生ADR (25.65%)多于其他年龄段;医院上报ADR 265例(98.52%);住院者207例(76.95%);静脉给药者241例,占总例数的87.01%;抗微生物药139例(44.27%);中药制剂83例(26.43%);ADR的临床表现,以全身反应为多(44.98%);皮肤及附件损害次之(36.80%)。结论:应加强ADR监测报告,促进临床安全、合理用药。更多还原

【Abstract】 Objective:To find the situation of ADR from hospitals and drug manufacturing enterprises and study some related factors of ADRs.Method:269 ADR cases were analyzed with the epiolermiological method in terms of the inpatient, age,sex,route administration,drug category and clinical manifestation,etc.Result:In 269 ADR cases,males were more than females,and the 20-29 year-old group was more than the other age groups in the ADR occurrence.265 cases (98.52%)were reported from the hospital,207 of them(76.95%)from inpatients,241 cases(87.01%)were involved in intravenous administration,139 cases(44.27%),related to antibiotics,and 83 cases(26.43%),related to traditional Chinese medicine injection.The clinical body symptomatic reaction accounted for 44.98%,and the skin lesion and their accessories, 36.80%.Conclusion:ADR monitoring should be strengthened to promote the rational drug use in the clinic.更多还原