【摘要】 目的:分析我院药品不良反应(ADR)发生特点和相关因素,确定来年 ADR 监测工作方向。方法:对我院2007年度收集到的462例 ADR 报告进行统计分析。结果:ADR 报告中20至59年龄段构成比最高;ADR 涉及的药品151种,其中抗感染类药物引起的 ADR 占总例数的74.68%(345例),中成药引起的 ADR 次之;静脉给药的 ADR 占72.08%(333例)是引起 ADR 的主要途径;临床表现以皮肤及其附件损害为主,其次是消化系统损害。结论:临床应重视 ADR 的监测和报告工作,促进合理用药、减少和避免 ADR 的发生。更多还原

【Abstract】 Objective:To analyze the characteristics and related factors of adverse drug reactions(ADRs)in our hospital and establish the way of clinical ADR monitoring in the next year.Method:A total of 462 ADR reports collected in 2007 were statistically analyzed.Result:Among the 462cases of ADR,the patients at the age of 20 to 59 had the highest incidence.The drugs that induced ADR totaled 151 kinds.74.68%(345cases)were induced by anti-infective drugs, followed by traditional Chinese drug preparations;72.08%(333cases)were induced by intravenous injections.ADRs were mainly manifested in skin and local lesions,next in alimentary system lesions.Conclusion:In order to reduce and avoid the occurrence of ADR and promote the rational use of drugs,clinical departments should attach great importance to the mo- nitoring and report of ADR.更多还原