【摘要】 目的探讨脑肿瘤术中自体组织修补硬脑膜缺损的取材和应用技巧。方法回顾性分析2000年7月至2006年12月间,在我院行脑肿瘤术中硬膜修补的患者的临床资料,总结自体组织和人工生物材料修补应用的方法、效果、并发症等。结果共实施手术999例,其中122例患者用其自体头皮帽状腱膜下层、颅骨骨膜、大腿阔筋膜及硬脑膜外层修补,术中硬脑膜缺损均满意修复,无感染、头皮下积液、脑脊液漏等并发症,随访6个月以上无不良反应。43例用人工生物材料修补的患者,有2例出现发热、头皮炎症反应,需二次手术取出。结论自体组织经济实用,并发症少,基本上可以满足硬脑膜修补的需要,临床上应尽量采用。更多还原

【Abstract】 Objective To investigate the sources and techniques of dural reconstruction with autologous tissues. Methods Results 999 cases operated during, Of the 165 cases with dural defects,122 cases were reconstructed with autologous subgaleal layer, cranial periosteum, fascia lata of thigh or outer layer of dural mater, respectively. All the dural defects were reconstructed satisfactorily without infection, subscalp hydrop or cerebrospinal fluid leakage. With more than 6 months follow-up, there was no harmful reaction; Compared with the 43 cases of reconstructed with artificial biomaterial, 2 cases were found fever, scalp inflammation and the artificial biomaterial were taken out of by second operation. Conclusion Being easy obtained and practical, autologous tissues should be the first choice for reconstruction of the dural defects when it is needed in clinic.更多还原