【摘要】 目的:制备平心颗粒并建立其质量控制标准。方法:采用高效液相色谱法测定丹参中的丹参素含量,HPLC的色谱柱为C₁₈（150mm×4.6mm,5μm）,流动相为甲醇-水-磷酸（15:85:0.014 2）,检测波长为280nm,流速为1.0mL·min^-1。结果:丹参素在进样量0.28～1.4μg线性关系良好,r=0.996 4,平均回收率为98.4%,RSD=0.79% （n=3）。结论:处方合理,制备工艺可行,质控方法专属性强、重现性好,可作为平心颗粒的质量控制标准。更多还原

【Abstract】 Objcetive:To prepare Pingxin granules and establish its quality control standards.Methods:Rhizo- ma coptidis and the content of salvia miltiorrhiza’s salvia miltiorrhiza was determined by HPLC in the Pingxin granule. HPLC was applied with a C₁₈column,and the mobile phase of methanol-1% Acetic acid solution（15:85:0.014 2）, and the detection wavelength was 280nm,and the flow rate was 1.0mL·min^-1.Results:Ferulie acid showed a good linear relationship at a range of 0.28～1.4μg,r=0.996 4.The average recovery was 98.4%,RSD=0.79%（n= 5）.Conclusion:The formula was reasonable,the preparation method was feasible,and the quality control methods have high selectivity and good reproducibility,which can be used as the quality control methods of Pingxin granules.更多还原