【摘要】 3-氯-6-肼基哒嗪分别与乙酰丙酮和3-二甲胺基丙烯醛反应,合成了中间体3-氯-6-(3,5-二甲基-1H-吡唑-1-基)哒嗪(2)和3-氯-6-(1H-吡唑-1-基)哒嗪(4),它们与多种取代苄醇反应,得到了一系列未见报道的3-取代苄氧基-6-(取代-1H吡唑-1-基)哒嗪,其结构均经1HNMR,IR和元素分析确证.初步的生物活性测试结果表明,所合成的化合物对油菜和稗草均具有一定的抑制作用.更多还原

【Abstract】 A series of novel 3-(substituted benzyloxy)-6-[(un)substituted 1H-pyrazol-1-yl] pyridazine de-rivatives were synthesized through the condensation of various substituted benzyl alcohols with 3-chloro-6-(3,5-dimethyl-1H-pyrazole-1-yl)pyridazine(2) or 3-chloro-6-(1H-pyrazol-1-yl)pyridazine(4).2 and 4 were obtained from the cyclization of 3-chloro-6-hydrazinylpyridazine with acetoacetone and/or 3-dimethylamino acrolein.The structures of the title compounds were identified by 1H NMR,IR spectra and elemental analysis.Preliminary bioassay showed that all of them possessed some extent herbicidal activity against Brassica campestris and Echinochloa crusgalli.更多还原