【摘要】 目的了解结核菌-L型在复治难治(复难治)肺结核患者中所占的比例,以及对结核病疫情的影响。方法选择复难治肺结核患者现场拍摄X光胸片,晨痰作结核菌和结核菌-L型培养。结果在260例复难治肺结核患者痰标本中,检出结核菌阳性92例;92例结核菌阳性患者中,检出结核菌-L型阳性32例,检出率为34.8%。168例结核菌阴性患者中检出结核菌-L型阳性45例,检出率为26.8%。结核菌和结核菌-L型均阳性的患者,其X光胸片病变范围比结核菌和结核菌-L型均阴性的患者广泛(x~2=6.44,P<0.05);其肺部空洞也明显增多(x~2=31.63,P<0.01)。结论无论是菌阳还是菌阴结核病患者,都可检出结核菌-L型;结核菌和结核菌-L型合并感染,可导致患者双侧肺病变加重、空洞增多。更多还原

【Abstract】 Objective To investigate the ratio of L-form of Mycobacterium tuberculosis (TB-L) infection in recur- rent pulmonary tuberculosis (TB) patients and its effect to pulmonary lesions and epidemic situation of tuber- culosis.Methods The X-ray chest films of the recurrent pulmonary tuberculosis patients were photographed in situ and analyzed,and the patients’ morning sputum were cultivated for TB and TB-L.Results There were 92 TB-positive cases in 260 recurrent pulmonary tuberculosis patients.In 92 TB-positive cases,32 TB-L positive cases were detected with positive detection rate of 34.8%.There were 45 TB-L positive cases in 168 recurrent pulmonary tuberculosis patients whose sputum were tuberculosis negative and the TB-L positive detection rate was 26.8%.The data also demonstrated that the pulmonary lesion extent of both TB and TB-L detection posi- tive patients was more extensive than those both negative patients (x~2=6.44,P<0.05).Additionally pul- monary cavity significantly increased in both TB and TB-L detection positive patients (x~2=31.63, P<0.01).Conclusion These results suggest that TB-L could be detected in TB positive or TB negative pa- tients.TB co-infection with TB-L may aggravate bilateral pulmonary lesions and increase cavities.There are 26.8% TB-L positive patientsin TB negative patients,therefore their treatment and impact on epidemic situa- tion should no be,igrored.更多还原