【摘要】 二脂酰甘油酰基转移酶2(Acyl CoA:Diacylgycerol Acyltransferase 2,DGAT2)是生物体内的一种非常重要的酶,其主要机制是使二酰甘油加上脂肪酸酰基辅酶A以共价健结合形成三酰甘油。编码该酶的基因有DGAT2和DGAT1。文章综述了DGAT2基因的发现、定位、结构、生物学效应及其遗传多态性与生产性能的关系,并对其应用前景进行了展望。更多还原

【Abstract】 Diacylgycerol acyltransferase2 (DGAT2) is an important enzyme in many organisms. DGAT2 catalyzes the final step of triacylglycerol (TAG) biosynthesis by converting diacylgycerol (DAG) and fatty acyl-coenzyme A (CoA) into TAG. This enzyme is encoded by both DGAT2 and DGAT1 genes. This paper reviews the discovery of the DGAT2 gene, its struc-ture, chromosomal location and biological effect. The relationship between its genetic polymorphisms and animal perform-ance traits is also discussed. The review ends with future prospects.更多还原