【摘要】 目的观察慢性心功能不全(CHF)患者血清甲状腺激素的变化,评估其临床意义。方法应用放射免疫法测定33例慢性心功能不全患者血清三碘甲腺原氨酸(T3)、甲状腺素(T4)、反三碘甲腺原氨酸(rT3)和促甲状腺激素(TSH),与11例正常人血清甲状腺激素水平进行对照分析。结果慢性心功能不全患者血清T3明显低于对照组(P<0.01),而血清rT3高于对照组(P<0.01或P<0.05)。血清T4和TSH与对照组相比差异无显著性(P>0.05)。结论慢性心功能不全患者血清T3下降、rT3升高,且与病情相关。其可作为诊断CHF指标,并可用于判断病情。更多还原

【Abstract】 Objective To investigate the changes of serum thyroid hormone in patients with chronic heart failure(CHF) and to define their clinical significances.Methods Radioimmunoassay was applied to determine the serum levels of T3,T4,rT3 and TSH in 33 CHF patients and 11 normal subjects.Results The T3 level was lower in CHF group than in the control(P<0.01),but the level of rT3 was higher(P<0.01 or 0.05).No differences in T4 and TSH levels were found between the CHF patients and the normal subjects.Conclusion T3 decreases and rT3 increases in the patients with CHF.They two are correlated with the degree of the heart failure,serving as the diagnostic index of CHF.更多还原