【摘要】 目的探讨轻度认知损害(MCI)老年病人多导睡眠图(PSG)变化特点,为早期诊断MCI提供依据。方法应用多导睡眠生理仪,采用眼电图和下颌肌电图及脑电图技术,对17例MCI老年病人(MCI组)的PSG进行全夜监测,并与18名正常老年人(NC组)对照。结果与NC组比较,MCI组睡眠总时间减少[NC组(38l±s37)min,MCI组(313±67)min,P<0.01],觉醒时间增加[NC组(30±9)min,MCI组(53±17)min,P<0.01],睡眠维持率下降[NC组(94±10)%,MCI组(85±13)%,P<0.05],第1阶段睡眠百分比增加[NC组(13.7±2.3)%,MCI组(28±10)%,P<0.01],第2阶段睡眠百分比降低[NC组(60±4)%,MCI组(51±18)%,P<0.05]和第3阶段睡眠百分比降低[NC组(9±5)%,MCI组(4±3)%,P<0.01],快眼动(REM)睡眠强度增强[NC组(21±4)%,MCI组(40±22)%,P<0.01]。结论PSG中的深度睡眠减少可能是MCI病人所具有的特定的电生理学指标之一。更多还原

【Abstract】 AIM To assess the changes on the whole night polysomnography(PSG)in aged patients with mild cognitive impairment(MCI).METHODS The whole night PSG were performed in 17 patients(MCI group)with MCI and 18 normal subjects(NC group)by Neurofax-PSG sleep instrument.RESULTS The total sleep duration,waking times,sleep efficiency,percentage of stage 1 sleep,percentage of stage 2, percentage of sleep stage 3 sleep and REM intensity were(381±s 37)min and(313±67)min,(30±9)min and(53±17)min,(94±10)% and (85±13)%,(13.7±2.3)% and (28±10) %,(60±4)% and (51±18) %,(9±5)% and (4±3)%,(21±4)% and(40±22)% in NC group and MCI group respectively.There were significant differences between two groups(P<0.01 or P<0.05).CONCLUSION The decrease in deep sleep of PSG might be one of specific electrophysiological indexes of MCI patients.更多还原