【摘要】 阿尔茨海默病是发生在老年期及老年前期的以进行性痴呆为主要特征的神经退行性病变,病因尚不明确,确诊靠脑组织活检或尸检。磁共振波谱成像可以无创性研究活体组织器官代谢、生化改变及化合物定量分析,目前应用较广泛的是氢质子磁共振波谱成像,为阿尔茨海默病的生化改变研究、早期诊断、鉴别诊断以及治疗提供了一种无创、灵敏的影像学方法。更多还原

【Abstract】 Alzheimer’s disease is a degenerative disease of brain characterized by progressive dementia which occurs during presenium and senectitude, and the cause of AD is still unknown. The final diagnosis depends on biopsy or autopsy of brain tissue. Magnetic resonance spectroscopy can study the metabolism, neurobiochemistry, and quantitive analysis of organs in vivo noninvasively. At present, proton magnetic resonance is applied more widely, which is a noninvasive and sensitive imaging technique for studying brain chemistry, early diagnosis, differential diagnosis and treatment.更多还原