【摘要】 目的:探讨不同给药时机氯诺昔康对妇科腹腔镜术后急性疼痛治疗的效果。方法:80例ASAI～II择期行妇科腹腔镜手术病人随机分成两组:A组于手术结束时静脉注入氯诺昔康8 mg,B组于麻醉诱导前静脉注入氯诺昔康8 mg,每组40例。两组均在病人完全清醒时(T0)、完全清醒后(T1)0.5小时、1小时(T2)、2小时(T3)、6小时(T4)、12小时(T5)、24小时(T6)各时点进行通气窒息敏感性(VAS)观察。结果:麻醉前及术后疼痛时注入氯诺昔康8mg均可使VAS降低,但麻醉前用药组VAS显著低于术后用药组(P<0.01)。结论:不同时机使用氯诺昔康对妇科腹腔镜病人术后急性疼痛的治疗效果,B组优于A组,提示氯诺昔康具有超前镇痛作用。更多还原

【Abstract】 Objective:To observe the effect of the time of lornoxican administration on postoperative analgesia in patients after laparoscopic gynecology surgery.Methods:Eighty patients with gynecology surgery were randomly divided into two groups,with forty cases in each group.The patients in group A received lornoxican 8mg after operatioin,and in group B lornoxican 8mg before induction of anesthesia.ASA in all patients was I~II.Postoperative pain was estimated by visual analogue scale(VAS).Results:The VAS was lower in group B than that in group A(P<0.01).Conclusion:Lornocxican administered before induction of anesthesia or after operation may relieve postoperative pain in patients undergoing laparoscopic gynecology surgery.It is more effective to inject loronxican before induction of anesthesia than that after operation.更多还原