【摘要】 研究苏木Caesalpinia sappan L.的化学成分。利用溶剂萃取,反复硅胶、凝胶柱色谱和反相硅胶等手段进行分离纯化,根据理化性质、波谱数据进行结构鉴定。分离并鉴定了14个化合物,分别为巴西苏木素(1),苏木酮B(2),(E)-3-(3,4-dihydroxybenzylidene)-7-hydroxychroman-4-one(3),3-去氧苏木酮B(4),brazilideA(5),1,7-二羟基口山酮(6),槲皮素(7),鼠李素(8),苏木查耳酮(9),3-去氧苏木查耳酮(10),butein(11),2,4,5-三羟基苯甲醛(12),3,8,9-trihydroxy-6H-benzo[c]chromen-6-one(13),β-谷甾醇(14)。化合物12和13为两个新天然产物,首次报道了化合物13的碳谱数据。化合物6为首次从豆科植物中分离得到,也是云实属分离得到的第一个口山酮类化合物。更多还原

【Abstract】 To study the chemical constituents of Sappan Lignum. Chemical constituents were isolated by method of solvent extraction,repeated chromatography with silica gel,Sephadex LH-20,and ODS. The structures were elucidated based on spectro-scopic data. Fourteen compounds were isolated and their structures were identified as brazilin (1),sappanone B (2),(E)-3-(3,4-dihydroxybenzylidene)-7-hydroxychroman-4-one (3),3-deoxysappanone B (4),brazilide A (5),euxanthone (6),quercetin (7),rhamnetin (8),sappanchalcone (9),3-deoxysappanchalcone (10),butein (11),2,4,5-trihydroxybenzaldehyde (12),3,8,9-trihydroxy-6H-benzo[c]chromen-6-one (13) and β-sitosterol (14). Compounds 12 and 13 were two new natural compounds,and the 13C NMR data of compound 13 were reported for the first time. Compound 6 was the first xanthone isolated from the genus Caesalpinia.更多还原