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心肌缺血预适应对急性心肌梗死静脉溶栓冠脉再通的影响

The effects of ischemic preconditionong on patency of infarct-relataed coronary artery in patients with acute myocardial infarction treated by intra-venous thrombolytic therpy

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【作者】 楚强邹杰

【Author】 CHU Qiang,ZOU Jie. Zhoukou City Central Hospital,Zhoukou 466000,China

【机构】 周口市中心医院心内科周口卫校基础教研室

【摘要】 目的探讨心肌缺血预适应对急性心肌梗死静脉溶栓治疗冠脉再通的影响。方法84例急性心肌梗死患者接受尿激酶静脉溶栓治疗,分梗死前有心绞痛组和梗死前无心绞痛组,依据临床间接血管再通标准观察两组再通情况,部分病例进行冠脉造影检查。结果两组再通率分别为74%和29.4%,差异有统计学意义(P<0.01)。结论心肌缺血预适应可提高急性心肌梗死静脉溶栓的冠脉再通。

【Abstract】 Objective To study the effects of ischemic preconditioning on patency of infarct-related coronary in patients with acute myocardial infarction(AMI) treated by intravenous thrombolytic therapy. Methods 84 cases of AMI receiving thrombolytic treatment with intravenous urokinase were divided into two groups:the one with preinfarcting angine pectoris and the other without, the patency rate of infarct-related coronary artery was assessed by uniform clinical criteria. Some cases of AMI were underwent coronary angiography. Results The patency rate of two groups was 74% and 29.4% respectively,showing significant difference(P<0.01). Conclusion Ischemic preconditioning may raise patency of infarct-related coronary artery in patients with AMI treated by intravenous thrombolytic therapy.

  • 【文献出处】 中国心血管病研究 ,Chinese Journal of Cardiovascular Review , 编辑部邮箱 ,2008年07期
  • 【分类号】R542.22
  • 【被引频次】4
  • 【下载频次】59
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