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高血压病患者24小时平均脉压与左室肥厚关系的临床研究

Clinical research of the relationship between 24 h average pulse pressure and left ventricular hypertrophy in essential hypertensive patients

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【作者】 刘志远肖培育李静门永忠

【Author】 LIU Zhi-yuan,XIAO Pei-yu,LI Jing,et al.Department of Cardiology,Nanyang Central Hospital,Nanyang 473009,China

【机构】 南阳市中心医院心内科南阳市中心医院心内科

【摘要】 目的探讨高血压病(EH)患者24h平均脉压(APP)与左室肥厚(LVH)的关系。方法对90例高血压病患者进行24h动态血压监测及心脏超声检查,根据有无LVH分为两组:LVH组和非LVH组,再以PP≥60mmHg、PP<60mmHg分为2个亚组。结果LVH组与非LVH组24hAPP分别为(76.3±16.5)mmHg和(56.3±10.6)mmHg,收缩压分别为(156.4±7.26)mmHg和(146.7±11.0)mmHg,差异均有统计学意义(P<0.05);而两组舒张压分别为(92.5±5.17)mmHg和(90.2±6.25)mmHg,差异无统计学意义(P>0.05);PP≥60mmHg组LVH发生率较PP<60mmHg组显著增加(P<0.01)。结论高血压患者24hAPP与LVH密切相关,脉压增大是心血管病的危险因素。

【Abstract】 Objective To investigate the relationship between average pulse pressure(APP) of 24 h ambulatory blood pressure monitor(ABPM)and left ventricular hypertrophy(LVH)in essential hypertensive(EH)patients. Methods 90 EH patients received examinations by 24 h ABPM and echocardiogram. They were divided into groups with or without LVH, and high PP(PP≥60 mm Hg)and low PP(PP<60 mm Hg)groups. Results 24 h APP and systolic blood pressure was higher in patients with LVH than that without LVH(P<0.05). But there was no significant differences of diastolic blood pressure in two groups(P>0.05). LVH were more common in high PP group than in low PP group(P<0.01). Conclusion LVH occurrence is related to 24 h APP in patients with EH. The increase of PP is a risk factor for cardiovascular diseases.

【关键词】 高血压肥大,左心室脉压
【Key words】 HypertensionHypertrophy,left ventricularPulse pressure
  • 【文献出处】 中国心血管病研究 ,Chinese Journal of Cardiovascular Review , 编辑部邮箱 ,2008年02期
  • 【分类号】R544.1
  • 【被引频次】4
  • 【下载频次】73
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