【摘要】 目的观察和分析非穿透小梁手术联合丝裂霉素C及深层巩膜反折引流治疗开角型青光眼的临床效果。方法对12例16眼开角型青光眼患者行非穿透小梁切除手术,术中联合应用丝裂霉素C及深层巩膜反折引流。观察手术前、后的眼压、视力、视野、前房(前房角)变化及手术后滤过泡情况。随访3~18个月。结果术前平均眼压(27.93±7.62)mmHg(1kPa=7.5mmHg),术后3个月时为(14.62±3.53)mmHg,手术前、后眼压差异有显著统计学意义(t=11·82,P<0.001)。手术前、后视力及视野无明显改变。术后16眼均形成滤过泡,其中I型6眼,Ⅱ型9眼,Ⅲ型1眼。结论非穿透性小梁切除联合应用丝裂霉素及深层巩膜反折引流术是治疗开角型青光眼的一种安全、有效、经济和具有可重复性的新治疗方式。更多还原

【Abstract】 Objective To observe the clinical effect of non-penetrating trabecular surgery combineded with mitomycin C and deep sclera flap invagination in the treatment of open-angle glaucoma.Methods Sixteen eyes (12 cases) with open-angle glaucoma were performed non-penetrating trabecular surgery combined with using mitomycin C and deep sclera flap invagination during the operation.The vision acuity,visual field,intraocular pressure (IOP),anterior chamber (angle of anterior chamber) before and after operation,filtering bleb after operation were observed.All patients were followed up from three to eighteen months.Results The mean IOP before operation was (27.93±7.62)mmHg (1 kPa=7.5 mmHg),and (14.62±3.52)mmHg three months after operation,the difference between the both was statistically significant (t=11.82,P<0.001).Vision acuity and visual field had no significant changes after operation.All eyes formed filtering bleb.Of the total,type I filtering bleb in six eyes,type II in nine eyes and type III in one eye.Conclusion Non-penetrating trabecular surgery combineded with mitomycin C and deep sclera flap invagination is a safe,effective,economic and repeatable new treatment for open-angle glaucoma.更多还原