【摘要】 随着当今生物质谱技术的蓬勃发展,生物质谱已经成为分析,鉴定蛋白质、多肽、细胞因子等生物大分子的重要手段。笔者对基质辅助激光解吸离子化质谱(MALDI-MS),电喷雾离子化质谱(ESI-MS),飞行时间质谱(TOF-MS)和离子阱质谱(Ion trap-MS)等生物质谱的功能和应用以及现代生物质谱与液相(LC)、毛细管电泳(CE)和二维液相色谱(2D-LC)等联用技术的最新应用与进展作了简要的综述。更多还原

【Abstract】 With the development of biological mass spectrometry,it has become a key technique for analysis and identification of biomacromolecules including proteins,peptides,cell factor and so on.This review mainly focuseed on the major functions and applications of MALDI-MS,ESI-MS,TOF-MS and Ion trap-MS,and recent improvements and successful applications of LC,CE and 2D-LC combined with biological mass spectrometry.更多还原