【摘要】 目的:探讨Ca2+和组织氧分压与经络现象之间的联系。方法:波尔杂交母山羊10只,用盐酸氯丙嗪(0.85 mg/kg)镇静后,采用乙二胺四乙酸二钠(EDTA-Na2200μL,0.05 kg/mol)络合穴区局部组织Ca2+,用新型组织氧分压传感针检测山羊膀胱经经穴"肝俞""大肠俞""关元俞"及旁开非经穴处氧分压的变化趋势。结果:1)膀胱经经穴的Ca2+电位明显高于旁开对照点(P<0.05,0.01);2)膀胱经经穴的组织氧分压高于旁开对照点(P<0.01);3)注射EDTA-Na2后,经穴的氧分压较注射前及注射生理盐水均明显升高(P<0.01),且经穴的氧分压高于旁开对照点(P<0.01)。结论:膀胱经穴Ca2+电位明显高于各自旁开对照点;注射EDTA-Na2络合Ca2+后氧分压明显升高。更多还原

【Abstract】 Objective To explore the relationship between energy metabolism and meridian phenomenon.Methods Ten Boer hybridism goats mitigated under chlorpromazine(0.85 mg/kg,intramuscular injection) were subjected to the present study.Changes of oxygen partial pressure(PO2) in "Ganshu"(BL 18),"Dachangshu"(BL 25) and "Guanyuanshu"(BL 26) of Bladder Meridian and in 3 non-acupoints(3 cm apart from BL18,BL25 and BL26 separately on the unilateral side) were recorded by using a needle-type tissue oxygen tension sensor before and following local injection of EDTA-Na2(200 μL,0.05 kg/mol,for complexing Ca2+) and 0.9% saline.Results ① Compared with the corresponding non-acupoints,Ca2+ potentials in BL18,BL25 and BL26 were all significantly higher(P<0.05,0.01).② In comparison with the corresponding non-acupoints,the values of tissue PO2 of BL18 and BL26 were significantly higher(P<0.01).③ After injection of EDTA-Na2,PO2 values in both BL18,BL26,and their respective non-acupoints increased significantly in comparison with those of either injection of saline or their respective basal values(P<0.01,0.05).Compared with those of their corresponding non-acupoints PO2 values in both BL18 and BL26 increased markedly(P<0.01).Conclusion Ca2+ potential of the Bladder Meridian was significantly higher than that of non-acupoints,and after complexing Ca2+,PO2 in acupoints and non-acupoints increased markedly,suggesting that Ca2+ may play an important role in meridian signaling and production of acupuncture effect.更多还原