【摘要】 目的:研究Na+微电流检测在快速诊断良、恶性病变中的作用。方法:选择良性病变45例,恶性肿瘤15例。肉眼观察切取病变组织2份,同时进行冷冻切片与Na+微电流检测。检测后组织分别标记,10%福尔马林固定,石蜡切片观察。结果:与常规石蜡切片诊断比较,冷冻切片法符合率为100%,微电流检测法符合率为96.67%(58/60),对良性病变诊断微电流检测法符合率100%(45/45),恶性肿瘤符合率86.7%(13/15),做出诊断的时间早于冷冻切片20min以上。Na+微电流检测曲线良性病变一般在20μA上下移动,不超过30μA,恶性肿瘤在30μA以上,最高为65μA。结论:Na+微电流检测术中能快速准确地判定病变的性质,帮助术者实施手术。与冷冻切片法同步应用,两者可以相互印证,是手术中快速诊断的又一种新方法。更多还原

【Abstract】 Objective:To apply Na+ microcurrent detector for rapid pathological diagnosis during operation.Methods:A total of 60 specimens were collected,2 tissue blocks were selected in every specimen.One was used to detect Na+ microcurrent and the other was examined by freezing section.Both specimen blocks were examined by conventional paraffin section after 10% formalin fixation.The results were compared with each other.Results:The coincidence of freezing pathological diagnosis with paraffin section was 100%(45/45)in benign tumor and 100%(15/15)in malignant tumor.The coincidence of Na+ microcurrent diagnosis with paraffin section was 100%(45/45)and 86.7%(13/15)respectively.There was no significant difference between the two methods(P>0.05).The diagnosis with Na+ microcurrent detector was quicker than freezing pathological diagnosis by 20 minutes.The curve of Na+ microcurrent was different between benign and malignant tumor.The microcurrent of benign tumor was about 20 μA,not higher than 30 μA.While the microcurrent of malignant tumor was higher than 30 μA and the maximum was 65 μA.Conclusion:Na+ microcurrent detector is rapid and precise in judging benign and malignant lesion.It helps surgeons to define operational scope and confirm the result of freezing section pathological diagnosis when they are used synchronously.更多还原