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α1A受体阻滞剂治疗慢性前列腺炎的疗效观察

Study on efficacy of inhibitors of α1A-receptor in chronic prostatitis

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【作者】 郑立泉赵升田郭慧梅綦岩

【Author】 ZHENG Li-quan1,ZHAO Sheng-tian2,GUO Hui-mei1,QI Yan1(1.Dept.of Urology,Affiliated Hospital of Taishan Medical College,Taian 271000,China 2.Dept.of Urology,The 2nd Affiliated Hospital of Shandong University,Jinan 250033,China)

【机构】 泰山医学院附属医院泌尿外科山东大学第二医院

【摘要】 目的观察α1A受体阻滞剂治疗慢性前列腺炎的疗效。方法80例慢性前列腺炎患者被随机分为A、B两组,分别应用左氧氟沙星(A组)、α1A受体阻滞剂坦索络新和左氧氟沙星(B组)。观察其疗效并进行统计学分析。结果B组治疗前后前列腺症状评分(SFQ)、前列腺液常规、尿流率的改善率明显优于A组(P<0.01)。结论α1A受体阻滞剂对慢性前列腺炎有明显的治疗作用,可作为治疗慢性前列腺炎的有效药物。

【Abstract】 Objective: To evaluate therapeutic efficacy of inhibitors of α1A-receptor(tamsulosin) in chronic prostatitis.Methods: Eighty cases were divided into A and B groups randomly,and treated differently as the following.Cases of group A were treated with levofloxacin only and group B with tamsulosin and levofloxacin.Symptom frequency questionnaire(SFQ),prostaticus,uroflow were observed before therapy and 6 weeks after therapy.The cure rate was analysed statistically.Results: In 18 cases(56.25%) of group A,the symptom disappeared or improved,in 17 cases(33.13%),SFQ improved and in 15cases(46.88%),WBC disappeared or lowered in EPS.In group B,the number was 32(88.89%),33(91.67%) and 30(83.33%).Conclusion: Inhibitors of a1A-receptor has obvious therapeatic efficacy in CP,bacterial or nonbacterial,and can be an effective drug for them.

【关键词】 慢性前列腺炎α1A受体阻滞剂疗效
【Key words】 chronic prostatitisα1A-receptorefficacy
  • 【文献出处】 泰山医学院学报 ,Journal of Taishan Medical College , 编辑部邮箱 ,2008年07期
  • 【分类号】R697.3
  • 【被引频次】4
  • 【下载频次】67
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