【摘要】 目的:评价地塞米松对罗哌卡因臂丛神经阻滞效果的影响。方法:45例择期或急症前臂及手部手术患者行腋路臂丛神经阻滞,ASAⅠ或Ⅱ级。随机分为3组,0.5%罗哌卡因30mL加地塞米松5mg(1mL),静脉注射生理盐水(NS)1mL(A组);0.5%罗哌卡因30mL加NS1mL,静脉注射地塞米松5mg(B组),0.5%罗哌卡因30mL加NS1mL,静脉注射NS1mL(C组)。结果:A组感觉、运动阻滞持续时间均长于B、C组(P<0.05),A组术后首次疼痛时间、镇痛持续时间明显长于B、C组(P<0.05),3组阻滞成功率为93%(14/15)、93%(14/15)和87%(13/15)。麻醉期间各组患者血流动力学均无明显改变。结论:地塞米松可以通过外周途径发挥镇痛作用,在0.5%罗哌卡因中加入5mg地塞米松可明显改善上肢手术臂丛神经阻滞效果,并可延长术后镇痛时间。更多还原

【Abstract】 Objective: To study the effect of dexamethasone added to ropivacaine on axillary brachial plexus block. Methods:Forty-five patients scheduled for hand and forearm surgery under axillary brachial plexus black were randomly al-located to three groups. Patients in group A received 0.5% ropivacaine 30 mL and dexamethasone 1 mL (5 mg) with normal saline 1 mL intravenously. Patients in group B received 0.5% ropivacaine 30 mL and normal saline 1 mL with dexametha-sone 1 mL (5 mg) intravenously. Patients in group C received 0.5% ropivacaine 30 mL and normal saline 1 mL intravenously. Results: The onset times of sensory and motor block were similar among the three groups. The duration of sensory blockade[(13.2±2.0)h versus (7.8±2.1)h and (7.5±1.9)h] and motor blockade [(11.7±2.3)h versus (7.6±1.8)h and (7.3±2.2)h] were significantly longer in group A than those of groups B and C ( P < 0.05). Conclusion: Dexamethasone added to ropivacaine 0.5% solution prolonged axillary brachial plexus blockade in the duration of sensory and motor block.更多还原