【摘要】 通过对12个产地辛夷挥发油进行气相色谱-质谱联用分析,建立不同产地、不同采收期辛夷药材质量控制方法。通过计算机谱库检索,其主要成分为1,8-桉叶素、芳樟醇、α-松油醇、石竹烯、α-依兰油烯、西柏三烯、异合金欢醇,不同批次药材成分含量有一定的差别,不同产地及不同采收期样品间有较大差异。通过色谱峰的相对保留值α和量化的面积归一化值C i两个参数实现了从图谱形式到数字形式的转换,其重叠率除5、6号较低外(小于75%),其余都较高,在75%~90%之间,从指纹图谱中提取13强峰、特征指纹等信息,方法重复性RSD小于1.05%,样品在48 h内稳定。更多还原

【Abstract】 An analytical method for Magnolia.was established based on gas chromatography-mass spectrometry(GC-MS) and 12 batches of Magnolia.from different sources and/or collection time were analysed.The main components were eucalyptol,linalool,α-terpineol,caryophyllene,α-muurolene,duvatrien and farnesol isomer.There were some differences in constituents and contents among those samples.The chromatogram was transformed into chromatograph fingerprints by two parameters,the chromatographic peak relative retention value α and the area normalization value Ci.Overlapping rate were between 75%-90%,except No.5 and No.6,the first 13 strong peaks and feature fingerprint were obtained from the chromatographic fingerprints,RSD of reproducibility was less than 1.05% and the sample was stable for 48 h.更多还原