【摘要】 综合利用1HNMR、13C NMR、DEPT、COSY、HMQC和HMBC等NMR技术,对从黄草乌中分离提取的粗茎乌碱类化合物进行了结构解析,分析结果表明,该化合物含有乌头生物碱化合物母核,以及1个甲氧基苯基片段和1个乙酸基片段,并最终确证该化合物为粗茎乌碱Ⅰ。根据该化合物特有的刚性特征,利用ROESY实验并辅以1D-GOESY等实验手段完成了该化合物的相对空间结构的解析。更多还原

【Abstract】 The structural elucidation of a compound isolated from Aconitum Vilmorrianum Kom,was investigated with NMR techniques including 1H NMR,13C NMR,DEPT,COSY,HMQC and HMBC.The results showed that the compound has an aconitine core,a methyl-oxy-phenyl segment and an acetyl segment.Based on the above results,the compound was finally confirmed to be CrassicaulineⅠ.The relative spatial configuraton of the compound was further elucidated with ROESY,1D-GOESY and other NMR techniques.更多还原