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炎痛舒搽剂抗炎镇痛的实验研究
Experimental Study on the Antiinflammation and Analgesia of Lotion of Yantongshu
【摘要】 目的为了观察炎痛舒搽剂的抗炎镇痛作用。方法采用二甲苯致小鼠耳廓肿胀、蛋清致大鼠足跖肿胀实验、小鼠腹腔毛细血管通透性实验观察炎痛舒搽剂抗炎作用;通过热板实验、压痛实验观察其镇痛作用。结果各项实验的药物中、高剂量组与模型组相比有明显差异(P<0.01或P<0.05)。结论该药有明显的抗炎镇痛作用。
【Abstract】 Objective To study the effect of anti-inflammation and analgesia of Yantongshu(YTS).Methods The animal model of auricular swelling was induced by dimethylbenzene in mice,hind paw swelling was induced by egg white,and twist reaction and celiac capillary hyperpermeability was induced by acetic acid in mice.Body twist reaction to hot-plate tail pressing was observed.Results Middle and high doses of YTS had significant inhibition on all the animal models(P<0.01 or P<0.05).Conclusion YTS has effect of anti-inflammation and analgesia.
【关键词】 炎痛舒搽剂;
抗炎镇痛;
【Key words】 Lotion of Yantongshu; Antiinflammation and analgesia; Experimental study;
【Key words】 Lotion of Yantongshu; Antiinflammation and analgesia; Experimental study;
- 【文献出处】 时珍国医国药 ,Lishizhen Medicine and Materia Medica Research , 编辑部邮箱 ,2008年10期
- 【分类号】R285.5
- 【被引频次】5
- 【下载频次】158