【摘要】 目的:探讨神经外科重症监护室(NICU)医院获得性肺炎的诱发因素、病原菌分布及其耐药性,为疾病的防治提供参考。方法:回顾性分析2003年至2005年73例医院获得性肺炎患者的临床资料,应用VITEK2系统进行细菌的鉴定及药敏试验。结果:最常见病原菌为革兰阴性菌,以铜绿假单胞菌、鲍曼不动杆菌和肺炎克雷伯菌为主;多重耐药现象明显。常见诱发因素为意识障碍、气管插管或气管切开和机械通气。结论:合理使用抗生素,保持呼吸道通畅,加强全身支持治疗是防治神经外科重症监护室医院获得性肺炎的有效手段。更多还原

【Abstract】 Objective To investigate the relevant factors,bacteria and drug resistance of hospital acquired pneumonia(HAP) in NICU for reference of its treatment.Methods The clinical information of 73 patients suffering from HAP in NICU in our department from 2003 to 2005 were analyzed by retrospective study.The identification and drug susceptibility tests of all bacteria were detected by VITEK2 SYSTEM.Results Pathogenic bacteria Gram-negatives(especially Pseudomonas aeruginosa,Acinetobacter baumannii and Klebsiella pneumoiae) were found in most of 73 cases,and the analysis of drug susceptibility showed multidrug resistance.Factors significantly predisposing HAP were consciousness depression,tracheal intubation or tracheotomy and mechanical ventilation(MV).Conclusion Selecting appropriate antibiotic,maintaining smooth airway and reinforcing therapy of systemic sustenance can effectively cure HAP in NICU.更多还原