【摘要】 目的:探讨胃肠道间质瘤(GIST)的临床表现、免疫组织化学(免疫组化)的特点及治疗方法。方法:对2001年7月至2007年6月收治的31例GIST患者的临床和治疗结果进行分析,并应用3种抗体(CD117、CD34、SMA)通过免疫组化方法进行分析研究。结果:GIST主要发生于胃、小肠、结直肠,CD117阳性表达率90.3%(28/31),CD34阳性表达率80.6%(25/31),SMA阳性表达率61.3%(19/31)。肿瘤切除率100%。结论:GIST的临床表现和组织学检查无特异性,CD117和CD34标记阳性是确诊GIST最有价值的诊断依据,手术切除是其主要的治疗手段。更多还原

【Abstract】 ObjectiveTo discuss the clinical diagnosis and surgery treatment of GIST.Methods31 patients with GIST were diagnoses by immunohistochemical staining, and surgery treated from July 2001 to June 2007.ResultsThe Gists originated in the stomach, the small intestine and colorectal.The positive rates of CD117, CD34,SMA were respectively. Conclusionthere are no specific clinical and histological characteristics of GISTs. CD117 and CD34 expression is most useful for the diagnosis. The resection is the major therapy.更多还原