【摘要】 目的分析鲍曼不动杆菌感染耐药情况及危险因素。方法对苏州大学附属第一医院2005年至2007年3年间院内获得性鲍曼不动杆菌肺炎患者耐药谱变化、感染因素进行回顾性分析。结果鲍曼不动杆菌对临床常用抗生素尤其是第3代头孢菌素耐药性逐年增加;重症监护病房患者在机械通气、介入导管的置入、激素及第3代头孢菌素的使用方面与普通病房患者之间的差异有统计学意义(P<0.05或<0.01)。结论为防止院内获得性鲍曼不动杆菌感染,应尽量减少机械通气和介入导管置入,加强护理,减少激素用量,合理使用抗生素,减少耐药菌株的产生。更多还原

【Abstract】 Objective To analyses resistant profile and risk factor of acquired infections of acine- tobacter baumanii. Methods The resistant patterns and risk factor of acquired infections of acineto- bacter baumanii were analysed by a retrospective analysis from the year 2005~2007 in the First Hospi- tal Affiliated to Suzhou University. Results The bacterial resistance rate to common antimicrobial a- gents increased by year; significant difference between patients in ICU, and in general ward, in me- chanical ventilation, intervening tube, glucocorticoid and ceftazidime treating was found. Conclusion The bacterial resistance rate of acinetobacter baumanii was increasing, It’s necessary to carry out inten- sive nursing, as far as possible reduce application the time of mechanical ventilation and intervening tube,and select reasonable antibiotic in order to reduce or delay resistance of bacteria to antimicrobial agents.更多还原