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可达龙对急性心肌梗死后再灌注心律失常的影响

Effect of Cordarone on Reperfusion Arrhythmia from Direct Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction

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【作者】 叶泽兵许楚宏赵雅红杜作义李克明

【Author】 YE Ze-bing,XU Chu-hong,ZHAO Ya-hong,et al.Department of Emergency,the 2nd People’s Hospital of Guangdong,Guangzhou 510317,China

【机构】 广东省第二人民医院急诊科广东省第二人民医院心内科

【摘要】 目的观察可达龙对急性心肌梗死(AMI)患者经皮冠状动脉介入治疗术(PCI)中再灌注心律失常(RA)的影响。方法选择符合诊断标准并有直接PCI指征的AMI患者129例,随机分为治疗组及对照组,对照组在常规药物治疗上行直接PCI,治疗组在上述治疗上加用可达龙,观察术后RA的发生情况。结果治疗组RA发生率(29.2%)明显低于对照组(53.1%),2组比较差异有统计学意义(P<0.01)。结论可达龙对RA尤其是室性心律失常有较好治疗和预防作用。

【Abstract】 Objective To investigate the effect of Cordarone on the reperfusion arrhythmias(RA) from direct percutaneous coronary intervention(PCI) in patients with acute myocardial infarction(AMI).Methods One hundred and five patients with presumptive clinical diagnosis of AMI agreeing with direct PCI were randomly divided into 2 groups.The control group received routine treatment,whereas the treatment group received additive Cordarone based on the routine treatment before the PCI.The incidence of RA was recorded.Results The incidence of RA was significantly lower in the treatment group(29.2%) than that in the control group 53.1%,and there was statistical difference between both groups.Conclusions Cordarone can effectively cure and prevent RA,especially ventricular arrhythmia in direct PCI of AMI.

  • 【文献出处】 中华全科医学 ,Chinese Journal of General Practice , 编辑部邮箱 ,2008年08期
  • 【分类号】R542.22
  • 【被引频次】2
  • 【下载频次】72
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