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米非司酮配伍甲氨喋呤治疗宫外孕临床分析

Clinical analysis of conservative treatment for ectopic pregnancy by using mifepristone combined with methotrexate

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【作者】 孟桂敏马娜欣甄亚萍陈书平赵玉捷张红玉

【Author】 MENG Gui-min1,MA Na-xin2,ZHEN Ya-ping3,et al.1 Maternal and Children Health Care Hospital of Xuanwu;2 Taoranting Hospital of Xuanwu;3 The Capital Hospital,Beijing 100054,China.

【机构】 北京宣武妇幼保健院北京市宣武区陶然亭医院首都医科大学北京宣武妇幼保健院 北京100054

【摘要】 目的探讨米非司酮配伍甲氨喋呤治疗宫外孕的临床疗效。方法米非司酮组44例,米非司酮配伍甲氨喋呤组45例。结果两者保守治疗宫外孕成功率有显著差异(P<0.01)。米非司酮配伍甲氨喋呤组血中β人绒毛膜促性腺激素(β-HCG)下降速度大于米非司酮组(P<0.01)。结论推荐使用米非司酮配伍甲氨喋呤进行宫外孕保守治疗。

【Abstract】 Objective To analyze the effectiveness of mifepristone combined with methotrexate for conservative treatment of ectopic pregnancy.Methods There were 44 cases in group of mifepristone and 45 cases in group of mifepristone combined with methotrexate.Results There was significant difference in successful rate of conservative treatment between these two groups(P<0.01).Serum level of β-HCG declined speedily in patients of group of mifepristone combined with methotrexate and it was faster than that of patients in group of mifepristone(P<0.01).Conclusion It is suggested to use mifepristone combined with methotrexate for conservative treatment of ectopic pregnancy.

  • 【文献出处】 临床和实验医学杂志 ,Journal of Clinical and Experimental Medicine , 编辑部邮箱 ,2008年03期
  • 【分类号】R714.2
  • 【被引频次】6
  • 【下载频次】91
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