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肾嗜酸细胞腺瘤的CT表现及病理基础

CT and Pathological Characteristics of Renal Oncocytoma

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【作者】 王芳陆菁菁秦明伟李明利任小波高鑫金征宇

【Author】 WANG Fang,LU Jing-jing,QIN Ming-wei,LI Ming-li,REN Xiao-bo,GAO Xin,JIN Zheng-yu (Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China)

【机构】 中国医学科学院中国协和医科大学北京协和医院放射科

【摘要】 目的总结肾嗜酸细胞腺瘤的CT表现及病理基础,提高肾嗜酸细胞腺瘤的诊疗水平。方法回顾性分析12例肾嗜酸细胞腺瘤患者的临床、影像和病理学资料。结果男7例,女5例,年龄40~65岁。均单侧单发,边界清晰。9例位于右肾。5例呈均匀等或略低密度,明显强化,7例中央可见瘢痕区。术前均诊断为肾癌,行肾切除术。肉眼观察肿瘤边界清楚,质地均匀。光镜下瘤细胞排列成腺泡管状或实性片状,无明显异型性和核分裂相。电镜下胞浆内见大量线粒体。结论肾嗜酸细胞腺瘤作为一种少见的肾脏良性腺瘤,其影像特征有助于术前诊断及指导治疗。

【Abstract】 Objective To summarize the CT findings and pathological foundation of renal oncocytoma,so that to improve the diagnostic accuracy of it.Methods The clinical data(including imaging and pathology) of 12 cases with renal oncocytoma were retrospectively analyzed.Results 7 cases were male and 5 cases were female,the age ranged from 40 to 65 years.All the tumors were single and unilateral with well-defined borders.The lesions in 9 cases were in right kidney.5 lesions were homogeneous iso-or hypodensity on plain CT scans and obvious enhancement on contrast-enhanced CT scans.Central scars could be found in 7 cases.All cases were diagnosed as renal cancer and nephrectomy were performed.Macroscopically,the tumor tissue showed clear margin,homogeneous texture.On light microscopy,the tumor cells were adenoid or laminar in pattern with very rare or no heteromorphism and mitosis.On electromicroscopy,enormous mitochondria were apparent.Conclusion The renal oncocytoma as a type of rare benign tumor,CT characteristics of it are helpful preoperative diagnosis and to guide surgical therapy.

  • 【文献出处】 实用放射学杂志 ,Journal of Practical Radiology , 编辑部邮箱 ,2008年09期
  • 【分类号】R737.11
  • 【被引频次】23
  • 【下载频次】329
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