【摘要】 目的探讨遗传性多发性骨软骨瘤(hereditary multiple osteochondroma,HMO)的临床及X线特点。方法分析经临床诊断及病理证实的5例HMO患者及调查其家系63人。结果63人中共21人患有HMO疾病,男16人,女5人。在5例病理证实的患者中,4例患者有明显的家族遗传病史,1例追访其家族三代成员无此病发生。结论遗传性多发性骨软骨瘤的发病具有显著的性别差异,且有典型的遗传倾向。瘤骨发生部位也具有家族倾向性,HMO具有隔代遗传的特点。更多还原

【Abstract】 Objective To investigate the X-ray and clinic manifestations of hereditary multiple osteochondroma(HMO).Methods Five patients with HMO clinically and pathologically confirmed and 63 persons in their pedigree were studied.Results Of 63 cases inquired in this study,there were 21 patients with hereditary multiple exostosis,including 16 men and 5 women.In 5 cases confirmed pathologically,4 patients had hereditary history of pedigree and the members of three generation in 1 patient with HMO had no the history of pedigree.Conclusion HMO has the remarkable sex difference and the typical inherited trend including the location of exostosis.HMO has inherited character of skipping generation.更多还原