【摘要】 目的:探讨PVB方案对晚期卵巢癌治疗的近期疗效。方法:对64例晚期卵巢癌病例回顾性分析。VCR1.5mgd1静推、NDP70mg/m2d2静脉滴注3小时以上,BLM30mgd3-d5静脉滴注。每3周重复1次,全组病例均治疗2疗程以上。结果:初治晚期卵巢癌患者有效率为45.8%,复治晚期卵巢癌患者有效率30.0%,有显著差异。初治患者的CR为4.2%,复治患者为零,无效达30%。不同部位肿瘤的疗效:盆腔肿瘤总有效率为63.2%、淋巴结转移为69.2%。最差为肝转移,稳定(SD)、无效(PD)分别为50.0%和37.5%。结论:PVB方案对晚期卵巢癌并发转移近期有一定疗效,毒副作用较小,具有临床应用价值。更多还原

【Abstract】 Objective:To research the short term curative effect of PVB regimen on late stage ovarian cancer.Methods: To review 64 cases of late stage ovarian cancer. VCR 1.5mg d1 intravenous injection, NDP 70mg/m2 d2 intravenous drip for over 3 hours, BLM30mg d3-d5 intravenous drip, repeated every three weeks and more than 2 courses for each case.Results: The effective rate on the cases untreated previously was 45.8%, on cases treated previously was 30.0%, which had noticeable difference. The CR of the cases antreated previousyl was 4.2%, and that of treated previously was 0, in which 30% are of no effect. Rate of with effect on cavum pelvis tumor was 63.2%, and of lymph node metastasis was 69.2%.Liver metastasis was the worst; the rates of SD and PD were 50.0% and 37.5% respectively.Conclusion:PVB regimen was with relatively low side effect, had a short term curative effect on late stage ovarian cancer and the metastasis.更多还原