【摘要】 目的:探讨肝癌三维适形放射治疗照射野的设计方法。方法:利用上海拓能(Topslane)公司的三维治疗计划系统对112例肝癌患者,根据医生要求的CTV和周围的敏感器官限制受量,进行三维适形放射治疗计划设计,结合剂量曲线分布情况和剂量体积直方图(DVH)选择最佳治疗方案。结果:以肿瘤中心点为剂量归一点,80%～90%的剂量线均能包绕靶区体积,而周围正常组织受量都在理想的范围内。结论:对肝癌的三维治疗计划设计时,要根据病人不同的病变部位采取不同的设野方法,这样能使靶区剂量分布均匀,适形度好,同时也有效地保护了敏感器官,从而提高肿瘤剂量及肿瘤局部控制率。更多还原

【Abstract】 Objective:To observe the field designing methods in 3-dimensional conformal radiation therapy(3D-CRT)for liver cancer.Methods:According to the limits of the CTV and neighbor sensitive organs’ absorbed dose to make 3D-CRT plans for 112 liver cancer patients by using Topslane’s 3-dimensional therapy plan system(TPS),and optimize the therapy scheme base on the dose curves and the dose-volume histogram(DVH).Results:To take the tumor’s center as the dose unitary point,target region was surrounded by 80%~90% dose lines and the normal organs’ absorbed dose was in desirable range.Conclusion:To plan a 3D-CRT for the liver cancer shonld adopt appropriate field design methods according to patients’ pathological changes position sensitive organs can be protected effectively,so can improve the tumor’s absorbed dose and local control rate.更多还原