【摘要】 目的探讨核素肾动态显像法测定肾小球滤过率在亲属活体肾移植供肾功能评价中的临床应用价值。方法30例亲属活体肾移植供体在手术前及术后3-12个月应用锝-二乙三胺五乙酸(99mTc-DTPA)肾动态显像法测定肾小球滤过率(GFR),对留存肾进行手术前后的比较,观察其代偿性变化。结果术后留存肾GFR为(58.4±12.1)ml/min,较术前留存肾(40.1±7.1)ml/min增加45.6%,但与术前双肾GFR(85.4±13.9)ml/min比较则下降31.6%。结论核素肾动态显像在亲属活体肾移植供肾功能及供者术后安全性评价等方面均有重要临床价值。更多还原

【Abstract】 Objective To explore the clinical value of renal dynamic scintigraphy for evaluating renal function in related-living donors. Methods 99mTc-DTPA renal dynamic scintigraphy were performed for determining GFR before and after kidney transplantation in 30 related-living donors. Results The residual kidney GFR increased by 45.6% compared with that before operation[(58.4±12.1)ml/min vs (40.1±7.1)ml/min],and decreased by 31.6% compared with total GFR before operation[(85.4±13.9)ml/min]. Conclusion Renal dynamic scintigraphy has an important clinical value for evaluating renal function and safety in related-living donors after kidney transplantation.更多还原