【摘要】 合成了1,10-二氮杂菲(phen)、加替沙星(HGA)与Nd(Ⅲ)的固态三元配合物,通过元素分析、红外光谱、1H NMR等确定了配合物的化学组成为Nd(phen)2(GA)3.H2O,配体phen及GA均以双齿螯合方式与金属离子配位,配位数为10.通过紫外光谱、荧光光谱初步研究了配合物及配体与DNA的作用.实验结果表明,配合物与DNA存在插入作用,阻止其复制或表达而起到抗菌作用.更多还原

【Abstract】 A novel ternary complex of Nd(Ⅲ) with 1,10-phenanthroline(phen) and gatifloxacin(GA) has been synthesized and characterized by elemental analysis,IR,1H NMR.The composition of complex Nd(phen)2(GA)3· H2O was determined.The ligands(phen and GA) are coordinated to the Nd(Ⅲ) ion in a bidentate chelating form,and the coordination number of metallic ion is ten.The spectra of fluorescence and UV showed that there are interaction between complex and DNA,The anti-microbial activity of this compound is probably related to this interaction.更多还原