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微波及高强电磁脉冲灭菌的机理分析

Study of Microorganism Sterilization by Instant Microwave And Electromagnetic Pulse

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【作者】 卢智远石频频朱满座孙文权丁华侯建强

【Author】 Lu Zhiyuan Shi Pinpin Zhu Manzuo Sun Wenquan Ding Hua Hou Jianqiang (Xidian University, Xi’an 710071,China)

【机构】 西安电子科技大学

【摘要】 采用连续微波与瞬态电磁脉冲对食用酱油和中草药丸进行灭菌实验研究,从微生物细胞的介电特性、膜离子通透率和外电场引起的膜电压变化进行了生物热效应和非热效应分析。微波连续波的灭菌主要是基于生物的热效应。而瞬态电磁脉冲灭菌则是基于生物的非热效应。在外电场作用下,细胞的跨膜电位增加,导致钾离子通道开启,细胞的钾离子流向膜外。膜电压的改变使得电压依赖性的钙离子通道开启。膜外浓度较大的Ca2+顺电位梯度进入细胞内,导致细胞消亡,细胞的跨膜电压变化越大,引起的细胞死亡率就越高。

【Abstract】 The sterilization effects of constant electromagnetic wave and instant pulse on foods and traditional Chinese medical pills are introduced in this paper. From the velum’s voltage variation caused by the outward electric filed,the dielectric properties of membranaceous ion and the pass rate of the membranaceous ion, we could analyze the biological heating effect and the biological non-heating effect. The sterilization effect of constant electromagnetic wave is based on the biological heating effect, while the instant electromagnetic pulse is based on the biological non-heating effect. With the applied electronic field, the voltage of membrane could increase, which results in the gates of K+ open, and the flowing out of K+. And the variation of the membranaceous voltage makes the gates of Ca2+ open. The Ca2+ of large consistency could come into the cell by the gradient of voltage. It could induce the death of the cells. The greater the variation of membranaceous voltage becomes,the higher will be the death rate of the cells.

【基金】 国家自然科学基金资助项目(30470429)
  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2008年04期
  • 【分类号】Q93
  • 【被引频次】12
  • 【下载频次】283
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