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基于多场耦合的生物组织微波热声信号分析

Microwave Thermoacoustic Signal Analysis of Biological Tissues Based on the Coupling of Multifield

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【作者】 陶春静宋涛刘国强阎静

【Author】 Tao Chunjing1,2 Song Tao1 Liu Guoqiang1 Yan Jing1 1(Institute of Electrical Engineering,Chinese Academy of Sciences,Beijing 100080,China)2(Graduate School of the Chinese Academy of Sciences,Beijing 100039,China)

【机构】 中国科学院电工研究所电磁生物研究组中国科学院电工研究所电磁生物研究组 北京100080中国科学院研究生院北京100039北京100080

【摘要】 我们根据微波照射生物组织时电磁场、热场、声波场三者之间的耦合关系,对微波激励热声成像正问题展开研究。从实验样本热学和声学的空间不均匀性角度出发,应用有限元方法求解热声波传播方程。由于入射微波对不同组织的穿透深度不同,不同组织对微波能量的吸收率不同,导致样本内部初始热声源的位置不同,相应地影响到声压传播情况。仿真结果表明,不同检测点声压信号中的信息量是不同的,检测点的声压信号富含样本中组织结构和电声学特性的信息量,从而能够从检测点的信号反映出关于样本结构和组成的信息。

【Abstract】 According to the coupling relationship of electromagnetic field,thermal field and acoustic field during the time that microwave irradiates the biological tissues,we conducted a study on the microwave-induced thermoacoustic tomography forward problem.In the study,we started from the thermoacoustic wave propagation that incorporated the spatial inhomogeneities of thermal and acoustic properties,and we used a method based on the finite element to solve the thermoacoustic equation.As the penetration depth and the specific absorption rate changed with the microwave frequency in biological tissue,the hotspot position and value altered,so the pressure wave propagation and the detecting value would be influenced.By analyzing the simulation results,we found that different detection point has different information content.Because the microwaveinduced acoustic waves contain abundant information about the structural,electromagnetic and acoustic properties of phantom,they can reflect information on the tissue composition and structure of the phantom effectively.

【基金】 中国科学院知识创新工程项目资助(KJCX1-09)
  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2008年01期
  • 【分类号】R310
  • 【被引频次】1
  • 【下载频次】132
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