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双歧啤酒对小鼠免疫功能的影响

Effect of Brewing Bifidobeer on Immunological Function of Mice

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【作者】 穆小萍张德纯邱建蒲荣

【Author】 MU Xiao-ping,ZHANG De-chun*,QIU Jian,PU Rong (Province-state Key Laboratory of Clinic Medicine, Ministry of Education, Office of Pathogenic Biology, Chongqing University of Medical Sciences, Chongqing 400016, China)

【机构】 重庆医科大学临床检验诊断学省部共建教育部重点实验室 重庆医科大学病原生物学教研室重庆医科大学临床检验诊断学省部共建教育部重点实验室重庆医科大学病原生物学教研室重庆400016

【摘要】 目的:研究双歧啤酒对小鼠免疫功能的影响。方法:将小鼠随机分成纯净水对照组、市售啤酒对照组和双歧啤酒低、中、高三个剂量组,剂量分别为25、50、100ml/kgbw,饮水法喂饲小鼠,测定小鼠胸腺和脾脏重量、腹腔巨噬细胞吞噬功能、血清溶血素抗体水平、皮肤迟发型超敏反应(DTH)程度。结果:与对照组比较,双歧啤酒高、中剂量组能显著增强巨噬细胞吞噬功能,增加血清溶血素抗体水平和DTH程度。结论:双歧啤酒能提高机体的免疫功能。

【Abstract】 Objective: To explore the effect of brewing bifidobeer on immuniological function of mice. Methods: Mice were randomly assigned to 5 groups: the purified water control group, the ordinary beer control group and three brewing bifidobeer groups(drunk the purified water containing brewing bifidobeer 25,50,100 ml/kg bw). The weight of thymus and spleen, the phagocytic capability of celiac macrophage, the level of serolysin and the degree of cutaneous delayed type hypersensitivity of mice were evaluated. Result: The phagocytic capability of celiac macrophage, the level of serolysin and the degree of cutaneous delayed type hypersensitivity of high dose and medium dosage brewing bifidobeer groups increased significantly compared with control groups. Conclusion: Brewing bifidobeer can enhance the immuniological function of mice.

【关键词】 双歧啤酒免疫功能小鼠
【Key words】 brewing bifidobeerimmuniological functionmice
【基金】 重庆医科大学科技创新基金项目(200533)
  • 【分类号】R151
  • 【被引频次】4
  • 【下载频次】105
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