【摘要】 大肠杆菌(Escherichia coil)L-鼠李糖(rha)调节子由三个功能相关的操纵子(operon)组成,位于大肠杆菌染色体基因组中。它编码大肠杆菌吸收和利用L-鼠李糖的蛋白,即一个鼠李糖运输蛋白(RhaT)、三个鼠李糖代谢酶(RhaB、RhaA、RhaD)以及两个调节蛋白(RhaS、RhaR)。三个操纵子均受到L-鼠李糖本身的诱导,同时以调控蛋白RhaS、RhaR和CRP(cAMP受体蛋白)为中介的正调控也参与调节。更多还原

【Abstract】 The rha regulon contains three function-associated operons,which located in the genome DNA.It encodes functions required for inducible uptake and utilization of L-rhamnose by Escherichia coil,including an active transport (L-rhamnose permease),three metabolizable enzymes (L-rhamnose isomerose,L- rhamnulokinase,L-rhamnulose-l-phosphate aldolase),and two regulatory proteins (RhaS,RhaR),which are induced by L-rhamnose,and positively controlled by RhaS,RhaR,and CRP(Cyclic AMP receptor protein).更多还原