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加味降脂理肝汤治疗痰瘀质非酒精性脂肪肝病63例

Clinical Observation of Modified "Jiangzhi Ligan Decoction" in Treating Non-alcoholic Fatty Liver Disease in Phlegm-Blood Stasis Constitution Patients

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【作者】 王亚平; 杨悦亚; 陈理书; 张志银; 要全保; 庄敏之; 胡南华; 朱艳; 郑昕; 周菲; 张迪; 郭兆玮;

【Author】 WANG Ya-ping1 YANG Yue-ya2 CHEN Li-shu3 ZHANG Zhi-yin1 YAO Quan-bao1 ZHUANG Min-zhi1 HU Nan-hua4 ZHU Yan1 ZHENG Xin1 ZHOU Fei1 ZHANG Di1 GUO Zhao-wei1 1.Branch of Shanghai First People’s Hospital Affiliated to Shanghai Jiao Tong University 2.Shanghai Literature House of Traditional Chinese Medicine 3.Shanghai Hospital of Integrative Chinese & Western Medicines 3.Shanghai University of Traditional Chinese Medicine

【机构】 上海交通大学附属第一人民医院分院; 上海市中医文献馆; 上海市中西医结合医院; 上海中医药大学; 上海交通大学附属第一人民医院分院 上海200081; 上海200020; 上海200082; 上海200081; 上海201203;

【摘要】 目的观察加味降脂理肝汤治疗痰瘀质非酒精性脂肪肝病的临床疗效。方法将120例非酒精性脂肪肝病患者随机分为对照组57例和治疗组63例。对照组予基础治疗(合理饮食及适当运动),治疗组在基础治疗上加用加味降脂理肝汤。两组均以3个月为1个疗程,治疗2个疗程;观察患者痰瘀体质项积分、体重指数、B超积分及肝功能、血脂变化。结果治疗组痰瘀体质项积分、体重指数、B超积分、肝功能、血脂等指标的改善情况均明显优于对照组(P<0.05或P<0.01)。结论加味降脂理肝汤能有效改善患者痰瘀体质,治疗脂肪肝病。

【Abstract】 Objective To observe the therapeutic effects of modified "Jiangzhi Ligan Decoction" in treating non-alcoholic fatty liver disease(NAFLD) in phlegm-blood stasis constitution patients.Methods One hundred and twenty patients of NAFLD were randomly divided into treatment group(n=63) and control group(n=57).Control group received elementary therapy including reasonable diet and appropriate movement.In treatment group,in addition to the elementary therapy,modified "Jiangzhi Ligan Decoction" was taken orally,twice a day.One course of treatment was three months,and both groups were treated for two courses.Symptom score,body mass index(BMI),B-ultrasonic examination,liver function,blood lipid were examined before and two courses after treatments.Results Compared with control group,the clinical symptoms,BMI,B-ultrasonic examination,liver function,blood lipid in treatment group were ameliorated more significantly after treatment(P < 0.05,P < 0.01).Conclusion Modified "Jiangzhi Ligan Decoction" is effective in treating NAFLD.

【基金】 上海市卫生局中医药科研基金资助项目(2005L003A)
  • 【文献出处】 上海中医药杂志 ,Shanghai Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2008年06期
  • 【分类号】R259
  • 【被引频次】17
  • 【下载频次】218
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