【摘要】 目的探讨糖化血清蛋白(GSP)及1,5-脱水葡萄糖醇(1,5-AG)在妊娠期糖代谢异常诊断中的价值。方法对正常妊娠组、糖筛查异常组及糖耐量异常组进行空腹葡萄糖、口服葡萄糖50g筛选、GSP、1,5-AG测定。结果糖筛查异常组GSP水平为(154±18)μmol/L、糖耐量异常组GSP水平为(157±26)μmol/L,与正常妊娠组[(136±30)μmol/L]比较,差异有统计学意义(P<0.01)。糖筛查异常组和糖耐量异常组1,5-AG水平分别为(57.3±30.2)μmol/L、(45.2±25.7)μmol/L,显著低于正常妊娠组水平[(84.5±35.6)μmol/L,P<0.01]。结论GSP、1,5-AG可作为妊娠期糖代谢异常筛查及诊断指标。更多还原

【Abstract】 Objective To investigate the diagnostic value of glucosylated serum protein(GSP) and 1,5-Anhydro-D-glucitol(1,5-AG) in abnormal glucometabolism in pregnancy.Methods The fasting blood glucose(FBG),50 g glucose challenge test(GCT),GSP,1,5-AG in normal pergnancy group,abnormal GCT pergnancy group and abnormal oral glucose tolerance test(OGTT) pregnancy group were determined.Results The levels of GSP in abnormal GCT pregnancy group and abnormal OGTT group were(154±18)μmol/L,(157±26)μmol/L respectively,and they were significantly higher than that in normal pregnancy group([136±30]μmol/L,P<0.01).The levels of 1,5-AG abnormal GCT pregnancy group and abnormal OGTT group were(57.3±30.2) μmol/L and(45.2±25.7)μmol/L respectively,and they were significantly lower than that in normal pregnancy group([84.5±35.6]μmol/L,P<0.01).Conclusions GSP and 1,5-AG are indicators for screening and diagnosing pregnant glucometabolism abnormality.更多还原