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分子吸附再循环系统治疗重型肝炎疗效及影响因素分析

Effect of MARS on severe hepatitis and its related factors

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【作者】 赵秀华张景遥宋修光王晓花邵飞陈士俊

【Author】 ZHAO Xiu-hua,ZHANG Jing-yao,SONY Xiu-guang,WANG Xiao-hua,SHAO Fei,CHEN Shi-jun(Jinan Infectious Disease Hospital,School of Medicine,Shangdong University,Jinan 250021,China)

【机构】 山东大学济南市传染病医院山东大学济南市传染病医院 济南250021济南250021

【摘要】 目的分析MARS(分子吸附再循环系统)治疗重型肝炎的疗效及影响因素。方法在综合治疗的基础上对123例重型肝炎患者进行MARS治疗,分析其疗效及重型肝炎的临床分型、分期、患者年龄、治疗次数对疗效的影响。结果MARS治疗重型肝炎123例,治愈或好转48例,治愈好转率39%。MARS对早、中、晚期重型肝炎的治愈好转率分别为80.8%、46.5%、13%,对急性、亚急性、慢性重型肝炎的治愈好转率分别为14.3%、55.6%、42.9%。MARS治疗重型肝炎疗效与治疗次数不呈正相关,与患者的年龄有关。结论MARS是治疗重型肝炎的有效方法,其疗效与患者年龄、重型肝炎的临床分型及分期有关,与MARS治疗次数不呈正相关。

【Abstract】 Objective To analyze the treatment effects of the molecular adsorbent recycling system(MARS) for severe hepatitis and the related factors.Method 123 patients with severe hepatitis were subjected to MARS as well as basic treatments. The effects of MARS and the related factors,such as the clinical types and stages of severe hepatitis,age of patients,and treatment times were analyzed.Result 48 patients were cured or improved(39%).The cure rates of early,mediate and advanced severe hepatitis were 80.8%,46.5% and 13% respectively and of acute,sub-acute and chronic severe hepatitis were 14.3%,55.6% and 42.9% respectively.The treatment effects of MARS had no positive relationship with the treatment times,but had some relationship with age.Conclusion MARS is effective in treating severe hepatitis,which is related to the age of patients and the clinical type and stage of severe hepatitis but not to the treatment times.

【关键词】 MARS肝炎,重型疗效影响因素
【Key words】 MARSHepatitis,severeEffectFactors
  • 【文献出处】 山东大学学报(医学版) ,Journal of Shandong University(Health Sciences) , 编辑部邮箱 ,2008年02期
  • 【分类号】R575.1
  • 【被引频次】3
  • 【下载频次】58
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