【摘要】 目的:评价一种新型栓塞材料(三羟甲基-丙烯酸微球)在鼻咽和鼻窦纤维血管瘤介入治疗中的有效性。方法:经股动脉穿刺,导管进入一侧或两侧颈外动脉供血血管,以直径100～500μm三羟甲基-丙烯酸微球栓塞肿瘤供血动脉。栓塞后1～3d行外科手术切除。结果:栓塞后,11例接受手术完整切除,术中见肿瘤均有缩小,部分肿瘤已发生坏死,术中出血150～900mL(平均380mL)。均经病理确诊为纤维血管瘤。1例因肿瘤过大而未行切除,3个月后再次栓塞另一侧上颌动脉供血,未再发生鼻出血。结论:三羟甲基-丙烯酸微球可安全地栓塞鼻咽和鼻窦纤维血管瘤,栓塞后肿瘤可缩小,有利于手术切除。更多还原

【Abstract】 OBJECTIVE:To evaluate the effects of Trisacryl gelatin microspheres in the embolization of nasopharyngeal and nasal sinus angiofibroma.METHODS:One or two feeding arteries branches of external carotid artery were embolized with Trisacryl gelatin microspheres in different diameter.The surgical operation was performed 1 or 3 days after the embolization.RESULTS:The angiofibroma was resected completely in 11 cases with blood lose from 150 mL to 900mL(mean 380 mL).In operation,the angiofibroma was found shrunk and had necrosis in some cases.The pathology of tumors was angiofibroma in all 11 cases.Another one without tumor resection received the second embolization 3 months later and there was no nosebleed recurred.CONCLUSION:The Trisacryl gelatin microspheres as a new material for embolization,can embolize the angiofibroma effectively and is helpful in the surgical resection with tumor shrunk and less blood lost.更多还原