【摘要】 目的探讨脐动脉血抵抗素和高敏C-反应蛋白(hs-CRP)对早产儿早期感染的诊断价值。方法将128例早产儿分为重度感染组48例、轻度感染组40例和对照组40例,检测3组早产儿的脐动脉血抵抗素和hs-CRP水平并进行比较。结果重度感染组早产儿的脐动脉血抵抗素和hs-CRP水平与轻度感染组和对照组间差异均有统计学意义(P<0.01);脐动脉血抵抗素水平与hs-CRP水平呈正相关(r=0.81,P<0.01)。结论脐动脉血抵抗素和hs-CRP检测对诊断早产儿早期感染具有重要意义。更多还原

【Abstract】 Objective To investigate reliable methods of diagnosing umbilical blood resistin and high-sensitive C-reaction protein(HS-CRP)in premature infants with early infection.Methods One hundred twenty-eight premature infants were divided into severe infection group(SI group,n=48),mild infection group(MI group,n=40)and control group(n=40).Levels of umbilical blood resistin and HS-CRP were determined and compared between the three groups.Results The early infection in premature infants was related to significant increase of concentrations of HS-CRP and resistin at birth time,and SI group was significantly different from MI group and the control(P<0.01).The increase of umbilical resistin was positively correlated with the changes of HS-CRP level(P<0.01),and the coefficient of linear correlation was 0.81.Conclusion Umbilical blood resistin can be used as an early diagnostic marker for early infection,especially for severe ones,in premature infants.更多还原