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肝素对婴幼儿深Ⅱ度烧伤创面的治疗作用

Clinical effects of heparin on deep partial thickness infantile burn wound

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【作者】 李岩霍然孔祥红张志华周莉萍张宏图

【Author】 LI Yan①, HUO Ran, KONG Xiang-hong, et al.①Department of Burns and Plastic Surgery, Shandong Provincial Hospital, Jinan 250021, China

【机构】 山东省立医院烧伤整形美容外科济宁市第一人民医院烧伤整形科济宁市第一人民医院烧伤整形科 山东济南250021山东济南250021山东济宁272100

【摘要】 目的探讨肝素对婴幼儿深Ⅱ度烧伤创面的治疗效果。方法伤后24h入院的婴幼儿烧伤患者32例,3%~20%TBSA,以深Ⅱ度为主,随机分为2组,清创后试验组创面先用肝素钠湿敷,再用SD-Ag乳膏包扎,对照组应用SD-Ag乳膏包扎,1次/d,3d后改为半暴露。观察创面疼痛缓解、水肿消退、愈合时间等。结果试验组创面湿敷数分钟后疼痛明显减轻,水肿消退快,愈合时间明显少于对照组。结论肝素外用于婴幼儿深Ⅱ度烧伤创面能缓解疼痛,缩短愈合时间。

【Abstract】 Objective To investigate the therapeutic effects of heparin on deep partial thickness infantile burn wound. Method Thirty-two cases inflicted with 3%-20% TBSA deep partial thickness burn wound, after fresh wound were debrided and divided into two groups: the treating group’s cases were handled with heparin and SD-Ag cream, while the controlled cases were treated with SD-Ag cream, until the wound healing. Reliving pain edema, and the wound healing time were observed simultaneously. Results Pains were relieved after the wound handled with heparin; the wound healing time was much shorter in heparin area than in SD-Ag area(P<0.05). Conclusion Topical application of heparin to deep partial thickness burn wound may alleviate the progressive tissue damage, relive pain during early stage, and promote wound healing.

【关键词】 烧伤肝素婴幼儿创面愈合
【Key words】 Burn Heparin Infant Wound healing
  • 【文献出处】 实用医药杂志 ,Practical Journal of Medicine & Pharmacy , 编辑部邮箱 ,2008年05期
  • 【分类号】R726.5
  • 【被引频次】2
  • 【下载频次】48
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