【摘要】 目的探讨印迹细胞学在检查2型糖尿病患者干眼病中的应用价值。方法2型糖尿病组30例60眼与非糖尿病对照组25例50眼,采用印迹细胞学技术观察结膜上皮鳞状化生程度、杯状细胞密度。结果糖尿病组结膜上皮鳞状化生级别平均秩为64.27,对照组为44.98;糖尿病组杯状细胞密度为(72.62±45.81)个/毫米2,对照组为(116.04±38.29)个/毫米2。两组比较,均有显著性差异(P<0.05)。结论印迹细胞学在检查2型糖尿病患者干眼病中有特征性的表现,是一种无创、快速、简单易行且经济的眼表面疾病细胞学检查方法。更多还原

【Abstract】 Objective To evaluate the usefulness of impression cytology in diagnosing of dry eye in patients with type 2 diabetes.Methods Impression cytology was performed on 60 eyes with diabetic patients and 50 normal eyes.Conjunctival goblet cell density,conjunctival epithelial squamous metaplasia were evaluated respectively.Results In impression cytology,eyes of diabetic patients average order were 64.27 while the normal eyes,are 44.98,the goblet cell density in patients with type 2 diabetes were 72.62±45.81/mm2 while those in normal eyes were 116.04±38.29/mm2.Eyes of diabetic patients demonstrated a significantly higher grade of squamous metaplasia and lower goblet cell density(P<0.05) as compared with normal eyes.Conclusion The demonstrations of impression cytology in dry eye of diabetic patients are distinctive.Impression cytology is a noninvasive,quick,easy and inexpensive technique,being a useful tool for diagnosis of ocular surface diseases.更多还原