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继发性不育男性泌尿生殖道支原体感染状况与耐药性分析

Analysis of infections and drug resistance of mycoplasmas in urogenital system of secondary infertile males

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【作者】 谢小毛黄开淑李文华陈红娟张文权胡兰英

【Author】 Xie Xiaomao,Huang Kaishu,Li Wenhua,Chen Hongjuan,Zhang Wenquan,Hu Lanying Reproductive Medical Center,The First People’s Hospital of Changde City,Hunan Changde 415003,China

【机构】 常德市第一人民医院生殖医学中心

【摘要】 目的探讨继发性不育男性患者泌尿生殖系支原体的感染状况及其耐药性。方法采用支原体分离培养鉴定与药敏试剂盒,对继发性不育男性患者泌尿生殖系分泌物进行支原体分离培养鉴定与药敏测试。结果572例继发性不育男性患者,泌尿生殖系支原体培养阳性278例,阳性率为48.6%,其中解脲脲原体(Uu)占90.3%(251/278);人型支原体(Mh)占1.4%(4/278);Uu合并Mh占8.3%(23/278)。药敏试验表明:喹诺酮类耐药率最高,四环素类和大环内酯类耐药率最低。结论支原体感染是男性继发不育的重要危险因素,在支原体感染的治疗过程中,我们应根据药敏测试结果选择敏感抗生素。

【Abstract】 Objective To analyze the mycoplasmal infection and its drug resistance in the urogenital system of infertile males.Methods Mycoplasma was cultured and identified in the discharge from urogenital system of secondary infertile male,then its drug resistance was test by drugsusceptibility kit.Results Mycoplasma culture were found to be positive in 278 patients(48.6%),Among them,Ureaplasma urealyticum(Uu)infection account for 90.3%(251/278),Mycoplasma hominis(Mh) infection for 1.4%(4/278)and the combination of Uu and Mh for 8.3%(23/278);The drug resistance test show that mycoplasma was the most susceptibility to macrolides and tetracyclines,but in susceptibility to fluoroquinlones.Conclusion Ureaplasma urealyticum infection isan important risk factor in Secondary infertility of males.therefore,the susceptible antibiotics shoud be chosen according to the susceptibility test in the treatment of mycoplasmal infections.

【关键词】 男性继发性不育支原体感染耐药
【Key words】 malesecondary infertilityureaplasmainfectiondrug resistance
  • 【文献出处】 中国男科学杂志 ,Chinese Journal of Andrology , 编辑部邮箱 ,2008年09期
  • 【分类号】R698.2
  • 【被引频次】9
  • 【下载频次】73
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