【摘要】 目的探讨茶色素与激素、环磷酰胺联合治疗难治性肾病综合征(RNS)的疗效。方法将75例RNS患者随机分成治疗组与对照组2组,对照组采用激素与环磷酰胺治疗,治疗组在对照组基础上加用茶色素治疗。结果治疗组完全缓解率和总有效率分别为46.2%和88.3%,显著高于对照组的29.6%和54.9%(p<0.05),而不良反应发生率治疗组为36.8%,显著低于对照组的59.5%(p<0.05)。结论茶色素与激素、环磷酰胺联合治疗可提高难治性肾病综合征的临床疗效。更多还原

【Abstract】 Objective To observe the curative effect of tea pigment combined with glucocorticoid and cyclophosphamide to the refractory nephrotic syndrome.Methods 75 cases with refractory nephrotic syndrome were randomly divided into control group and therapy group.The cases in the control group were treated with glucocorticoid and cyclophosphamide and the cases in therapy group were added tea pigment.Results The complete remission rate and total effective rate of therapy group were 47.2 % and 88.19 % respectively,which were obviously higher than that of control group.And the rate of adverse effect of therapy group was obviously lower than that of control group.Conclusion Tea pigment combined with glucocorticoid and cyclophosphamide can facilitate the curative effect to the refractory nephrotic syndrome.更多还原