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三种用药方案预防急性化脓性阑尾炎术后感染的药物经济学评价
Pharmacoeconomics of 3 prophylactic medication schemes for septic acute appendicitis postoperative infection
【摘要】 目的:评价3种抗菌药物用药方案预防急性化脓性阑尾炎术后感染的疗效和经济性。方法:采用回顾性调查方法,对我院99例急性化脓性阑尾炎术后预防性应用A组(头孢噻肟+替硝唑)、B组(头孢哌酮舒巴坦钠+替硝唑)、C组(头孢匹胺+替硝唑)进行最小成本分析。结果:3组方案预防急性阑尾炎术后感染的疗效比较无统计学意义(P>0.05),其治疗成本分别为(1 909.36±358.19)元,(2 617.66±396.56)元,(3 490.27±885.96)元。结论:A组为这3组中最佳用药方案。
【Abstract】 Objective: To evaluate the economic efficacy of three antibacterials prophylactic medication schemes for septic acute appendicitis postoperative infection.Methods:Using the analytical method of retrospective review,a total of 99 patients with septic acute appendicitis were divided into 3 groups: Group A was assigned to receive Cefotaxime plus Tinidazole;Group B to receive Sulbactam + Cefoperazone plus Tinidazole;Group C to receive Cefpiramide plus Tinidazole.All 3 groups carried out cost minimization analysis.Results:Comparison of curative effect was not statistically significan in 3 prophylactic medication schemes for acute appendicitis postoperative infectiont(P>0.05),against respective costs of 1 909.36±358.19 yuan,2 617.66±396.56 yuan and 3 490.27±885.96 yuan.Conclusion:Scheme C is more cost-effective in acute appendicitis postoperative infection.
【Key words】 Acute appendicitis operation; Antibacterials; Preventive medication; Cost minimization analysis;
- 【文献出处】 农垦医学 ,Journal of Nongken Medicine , 编辑部邮箱 ,2008年04期
- 【分类号】R656.8
- 【被引频次】1
- 【下载频次】100